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How To Use Fioricet / Butalbital

This drug is prescribed to treat headaches caused by tension. Acetaminophen reduces the pain of headaches. Caffeine increases the effect of Acetaminophen. Butalbital is a sedative that reduces anxiety and induces sleepiness as well as relaxation.

You can take this medication with or without food, as prescribed by your doctor. Usually, it is taken every 4 to 5 hours. If you’re taking the liquid version of the medication be sure to determine the dosage using an instrument that is specifically designed for measuring.  Avoid using a regular spoon since you may not receive the right dosage.

The dosage will be based upon your health condition as well as your response to treatment. This medication is most effective if it is taken when the first sign of headache appears.  If you hold off until your headache is worsening the medication might not be effective. The medication can cause withdrawal symptoms, especially in the event that it was often used for a long period of time or at high doses. In these cases, withdrawal symptoms (such as vomiting or nausea and mental/mood disturbances and seizures) could occur if you suddenly stop taking the medication. 

To prevent withdrawal-related reactions, your physician may reduce the dose gradually. Inform your doctor of any withdrawal symptoms immediately. With its many benefits, however, this medication can also trigger an excessive desire for drugs (addiction). This risk is higher when you’ve had an addiction to substances or alcohol before.  Use this medication as directed to decrease the chance of becoming addicted. The medication is acetaminophen-based. Don’t take more acetaminophen than the recommended amount. 

(See also the Side Effects, the Drug Interactions & Warnings Sections.)

Talk to your doctor if observe an increase in the usage of this medication, an increase in headaches, or increasing the frequency of headaches, the medication isn’t working as well or you use the medication more than two headache episodes per week. Your doctor might need to alter your medication or include a different medication to help prevent headaches. You can take this medicine orally, by itself, or with food, as advised by your doctor usually between 4 and 5 hours, if you require it.

The dosage you take will depend on the health status of your body and the response you have to treat. The most effective medication when administered at the first signs of headache appears. If you wait to treat until your headache has become worse, it’s likely that the treatment will not be efficient. In order to avoid withdrawal, your doctor may decrease your dose slowly. It’s more likely to occur when you’ve been taking the drug for a long duration or in high doses.

If in case you are experiencing withdrawal symptoms you can consult your doctor. Although it can be beneficial for some, it can cause addiction. There is a higher risk of addiction when there is an addiction to alcohol or drugs (such as a high level of using alcohol and other drugs).

Take this medication according to the directions to reduce the risk of developing an addiction.   Inform your doctor if notice an increase in usage of this medicine. This could result in an increase in headaches, and an increasing frequency of headaches or the medication isn’t working as it should or is being used for more than two episodes of headache each week. Do not take more than what is prescribed. Your physician may need to adjust your dosage or you may need to take additional medication to avoid headaches.

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Tell your doctor or pharmacist before you take this medication if you are allergic to acetaminophen or caffeine; or other barbiturates. (such phenobarbital or xanthine derivatives) and if you have any other allergies. Inactive ingredients can cause allergic reactions and other problems. For more information, consult your pharmacist.

Fioricet side effects symptoms may be nausea, vomiting, dry stomach, constipation, and trouble sleeping. If any symptoms persist or worsen, consult your doctor or pharmacist immediately. Take your time when standing up from a lying or sitting position to reduce the risk of dizziness and lightheadedness.

You should let your doctor know that you have been prescribed this medication. They may have determined that it is worth more than the possible side effects. Most patients who take this medication do not experience any side effects.

You should immediately contact your doctor if you experience any of the following side effects: mental/mood changes, fainting seizures, rapid/irregular heartbeat, or other symptoms.

It is rare to have a severe reaction to this medication. If you have symptoms such as swelling, itching, rash, dizziness, or difficulty breathing, you should immediately seek medical attention.

List of Some Common Side Effects of Butalbital:

  • Vomiting
  • Stomach pain
  • Lightheadedness
  • Dizziness
  • Sedation is the loss of awareness
  • Breathlessness
  • Nausea
  • Feeling “high” or intoxicated

Other adverse Effects:

  • Seizures
  • Confusion
  • Headache
  • Anxiety
  • Shaking
  • Extreme sweating
  • Fast heart rate
  • Muscle weakness
  • Trouble swallowing

These are not all possible side effects. If you have any additional symptoms, your doctor can help.

In the USA Contact your doctor for medical advice regarding side effects. What else you can do you may report the side effects to FDA at www.fda.gov/medwatch or contact them at 1-800-FDA-1088.

In Canada, you can contact your doctor for medical advice about side effects. Health Canada can be reached at 1-866-234-2233 to report side effects.

Drug interactions can alter the way your medication functions or increase your chance of side effects. This is not an exhaustive list of possible interactions between drugs.

Darunavir and sodium oxy bate medications can interact with this medication. These drugs alter liver enzymes and eliminate the drug from your system.

You may experience an increase in the elimination of certain substances by taking the drug. This is because the drug affects liver enzymes.

These drugs include “blood thinners” such as warfarin, Doxycycline and estrogen felodipine, Quinidine theophylline, and some beta blockers, like metoprolol, corticosteroids, and prednisone.

If you are taking any other medication that may increase drowsiness, such as cough, pain relievers made from opioids (such hydrocodone, codeine), alcohol or marijuana (cannabis), or medicines for anxiety and sleep (such lorazepam, alprazolam, zolpidem, cyclobenzaprine, carisoprodol) or antihistamines (such a cetirizine and diphenhydramine).

You should always read the labels on medicines, such as cold and cough products. They may contain caffeine or other ingredients that can cause drowsiness.

Some beverages, such as colas, tea, coffee, energy drinks, and even tea, are high in caffeine. Talk to your pharmacist about how to safely use these products.

Talk to your doctor or pharmacist about whether you should use other reliable methods of birth control in combination with this drug.

If you notice any bleeding or spotting, be sure to notify your doctor. These could indicate that your birth control method is not working correctly.

The medication could cause false results in laboratory tests. Make sure your doctors and lab personnel are informed about this medication.

You should inform your doctor or pharmacist before you start taking this medication if you are allergic to caffeine, butalbital, and acetaminophen, as well as to various barbiturates (such phenobarbital), or derivatives (such as theophylline), or to any other substances.

There may be inactive ingredients that could cause allergies or other problems. For more information, consult your doctor.

Before you begin using this medicine, consult your doctor or pharmacist about your medical history. This includes any severe respiratory problems (such as bronchopneumonia), or a specific disease (porphyria).

Also, discuss your family and personal history of substance abuse disorders (such as overuse of alcohol/drugs, mental/mood problems, or stomach/abdominal issues (such as stomach ulcers).

You may feel dizzy or sleepy from the drug. You could feel more dizzy or drowsy if you use alcohol or marijuana (cannabis).

You should not drive, operate machines or do anything that requires alertness until you can safely perform it. Avoid alcohol-based beverages.

If you are considering using cannabis, talk to your doctor. Some liquid products may contain alcohol, sugar or aspartame.

You should be cautious if you have alcohol dependence, diabetes liver disease, Phenylketonuria (PKU), or any other medical condition that requires you to limit or eliminate these ingredients from your diet.

Discuss safe use with your pharmacist or doctor.

Before you have surgery, or any other surgical procedure (such as a stress test, or procedure to restore normal rhythm in the event that an abnormally fast heartbeat occurs),

Inform your doctor or dentist about this medication and all products (prescription and nonprescription medications and herbal supplements) before you go.

Older adults might be more sensitive than younger ones to side effects such as drowsiness and difficulty sleeping. While Pregnancy this medication should only be used when it is absolutely necessary.

It is not recommended to use it for extended periods of time or in large quantities prior to delivery and it could also cause harm to the baby.

For more information, consult your doctor. If a mother has been on this medication for a long time, children may have withdrawal symptoms such as persistent crying, irritability, nausea, vomiting, seizures, or diarrhea.

If you notice any symptoms in your baby which are mentioned above, contact your doctor immediately.

This drug may be absorbed in Breast milk that could have adverse effects on the infant who is nursing. Before you start breastfeeding, consult your doctor.

Fioricet rating summary

8.7/10 average rating
8.5/10

247 ratings from 252 user reviews. Compare all 215 medications used in the treatment of Headache.

Fioricet reviews

What Our Customer Have to Say

I thought Fioricet is not addictive. Originally prescribed years ago for Sinus and Tension headaches, I now take 6 Fioricet pills everyday and find it manages my chronic daily headaches most days. I am very grateful for Fioricet medication.
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Kelvin Black
Dallas, TX, USA
4.5/5
To lessen or stop my daily migraines of 15 years for me FIORICET is the ONLY RX. I have tried many things but nothing works for me, Fioricet changed my life for the incredibly good. I have been lucky to have taken Fioricet pills that helped me so much.
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Zasha Swan
Hyrum, UT, USA
5/5
I have suffered from migraines for 37 years(I am 49). Fioricet was prescribed for the daily headaches afterward and has saved my daily existence. I now take them only as needed but am not addicted as some say. I agree that some drs want to not prescribe them lately and give you Xanax instead which is addictive. I'll take Fioricet for migraine.
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Linda Smith
Tamarac, FL, USA
4.4/5
I was first prescribed Fioricet for hormonal headaches during my pregnancy. It was so effective and helped ease the pain. It did make me drowsy. I've tried to avoid things that set off my headaches, like not eating before 2 pm, my pillows not being right when sleeping, brightness, sounds, smells, and stress. But some can't be avoided. Thank you.
women in grey doted dress Carmenita
Carmenita
Gambell, AK, USA
4.7/5

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Alagesic®¶
Americet®¶
Anolor®¶
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Brand names of combination products

Esgic® Plus (containing Acetaminophen, Butalbital, Caffeine, Codeine)
Geone® (containing Acetaminophen, Butalbital, Caffeine)¶
Orbivan® (containing Acetaminophen, Butalbital, Caffeine)¶
Fioricet® with Codeine (containing Acetaminophen, Butalbital, Caffeine, Codeine)
Phrenilin® with Caffeine and Codeine (containing Acetaminophen, Butalbital, Caffeine, Codeine)
¶This branded product is no longer on the market. Generic alternatives may be available.

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